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Clinical trials

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1,647 trials match your filters.
TrialSponsorPhaseStatusPrimary completion
To Evaluate the Effects of NMRA-335140 on Symptoms of Major Depression in Participants With Bipolar II Disorder.NCT06429722NMRAPhase 2Completed2025-04-09Actual
Inhaled Molgramostim in Pediatric Participants With Autoimmune Pulmonary Alveolar Proteinosis (aPAP).NCT06431776SVRAPhase 3Recruiting2027-06Estimated
A Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥5 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)NCT06431893TVTXPhase 3Enrolling by invitation2030-08Estimated
Safety Study of Cytisinicline in Adult Combustible and/or E-cigarette SmokersNCT06435221Achieve Life SciencesPhase 3Completed2025-09-29Actual
A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast CancerNCT06435429Jazz PharmaceuticalsPhase 3Recruiting2028-04-28Estimated
Phase 2 Study on the Pharmacokinetics and Safety of RLYB212 in Pregnant Women at Higher Risk for HPA-1a AlloimmunizationNCT06435845RallybioPhase 2Terminated2025-10-01Actual
A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous UrticariaNCT06445023Celldex TherapeuticsPhase 3Active not recruiting2026-10Estimated
Efficacy and Safety of Apitegromab for the Treatment of Adults Who Are Overweight or ObeseNCT06445075Scholar Rock, Inc.Phase 2Completed2025-03-04Actual
A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)NCT06455202Celldex TherapeuticsPhase 3Active not recruiting2026-10Estimated
A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)NCT06456580Vor BiopharmaPhase 3Recruiting2027-05Estimated
Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's DiseaseNCT06456593ABVXPhase 2Recruiting2026-12Estimated
Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial CancerNCT06463028Faeth TherapeuticsPhase 2Recruiting2028-09Estimated
Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL CancerNCT06463665Genelux CorporationPhase 2Recruiting2027-02Estimated
Safety, Pharmacokinetics and Efficacy of MBX 2109 in Patients With HypoparathyroidismNCT06465108MBX BiosciencesPhase 2Completed2025-05-23Actual
Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCLNCT06470451SoligenixPhase 3Terminated2026-05-22Actual
A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.NCT06481592IOVAPhase 2Recruiting2028-05Estimated
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic CardiomyopathyNCT06481891Lexicon PharmaceuticalsPhase 3Active not recruiting2027-01Estimated
A Study to Evaluate the Pharmacodynamics and Safety of ARCT-810 in Participants With OTCDNCT06488313Arcturus Therapeutics, Inc.Phase 2Recruiting2026-06-01Estimated
A Trial to Assess the Safety and Efficacy of Subjects With Dry Eye DiseaseNCT06493604ALDXPhase 3Completed2025-02-27Actual
Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular DegenerationNCT06495918OCULPhase 3Active not recruiting2027-01-08Estimated
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCLNCT06500273Allogene TherapeuticsPhase 2Recruiting2027-12Estimated
Study of ALTO-101 in Patients With SchizophreniaNCT06502964Alto NeurosciencePhase 2Recruiting2026-02Estimated
A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of Vonaprument (Formerly ANX007) in Participants With Dry Age-Related Macular Degeneration (AMD) With Geographic Atrophy (GA)NCT06510816ANNXPhase 3Active not recruiting2026-10-31Estimated
Efficacy and Safety of Oral Azelaprag Plus Once Weekly Tirzepatide Compared with Tirzepatide Alone in Participants with Obesity Aged 55 Years and OverNCT06515418BIOAPhase 2Terminated2025-02-06Actual
Vilamakitug in Spondyloarthritis Placebo-controlled Investigation for EfficacyNCT06526377XBITPhase 2Not yet recruiting2028-09Estimated
Safety and Efficacy of VDPHL01 in Males and Females With AGANCT06527365MANEPhase 2Active not recruiting2026-08Estimated
Pharmacokinetics Study of DESF in Adults With Oral Allergy SyndromeNCT06527937Aquestive TherapeuticsPhase 2Completed2024-10-10Actual
A Study to Evaluate the Efficacy and Safety of Abiprubart in Participants With Sjögren's DiseaseNCT06531395KNSAPhase 2Terminated2025-03-06Actual
Extension Study to Evaluate the Long-Term Safety and Tolerability of MBX 2109 in Patients With HypoparathyroidismNCT06531941MBX BiosciencesPhase 2Active not recruiting2027-05-27Estimated
The Clostridioides Difficile Trial of REC-3964NCT06536465RXRXPhase 2Terminated2025-05-06Actual

Primary completion marks the end of data collection for the main study measures, not a results publication date.