NCT06411899Phase 3Completed

A Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Study sponsor: MoonLake Immunotherapeutics AG

Compare the available registry edits below. Primary completion is the date data collection ends for the main study measures; it does not tell you when results will be published.

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Primary completion2025-09-02Actual

Enrollment · participants422Actual

Source updated2026-08-12Last update listed in the registry record

Version history

Changes to this trial

Last 12 months

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Posted 2026-06-08 · 3 fields changed

Completion date type changed

− Before

~~Estimated~~

+ After

Actual

Primary completion date changed

− Before

~~17 Jun 2025~~

+ After

2 Sep 2025

Recruitment status changed

− Before

~~Active not recruiting~~

+ After

Completed

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Study details

Conditions studied

Hidradenitis Suppurativa

Treatments or interventions studied

SonelokimabDrug
PlaceboDrug

Primary outcomes · main study measures

measure: Hidradenitis Suppurativa Clinical Response 75; description: Percentage of participants achieving Hidradenitis Suppurativa Clinical Response 75 (HiSCR75) where HiSCR75 is defined as at least a 75% reduction from baseline in abscess and inflammatory nodule (AN) count, with no increase from baseline in abscess or draining fistula count.; timeFrame: Week 16

History coverage

Research sample: selected versions from May 2023 onward plus a preceding baseline where available. Only selected fields were retained; endpoint measures were truncated to 300 characters. This is not complete trial or sponsor history. Daily snapshots begin when collection starts.

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