Research directory

Clinical trials

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1,647 trials match your filters.
TrialSponsorPhaseStatusPrimary completion
Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated MeningiomasNCT05130866RXRXPhase 2, Phase 3Terminated2025-08-18Actual
Study to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 in Patients With Relapsing Multiple SclerosisNCT05134441Immunic AGPhase 3Active not recruiting2026-11Estimated
Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC)NCT05136898URGNPhase 3Completed2023-02-02Actual
A Study of Adeno-Associated Virus Serotype 8-Mediated Gene Transfer of Glucose-6-Phosphatase in Patients With Glycogen Storage Disease Type Ia (GSDIa)NCT05139316RAREPhase 3Completed2024-02-20Actual
OASIS-HAE: A Study to Evaluate the Safety and Efficacy of Donidalorsen (ISIS 721744 or IONIS-PKK-LRx) in Participants With Hereditary Angioedema (HAE)NCT05139810IONSPhase 3Completed2023-11-09Actual
A Study to Evaluate Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx) in Patients With Polycythemia VeraNCT05143957IONSPhase 2Completed2025-06-26Actual
A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Regularly Transfused, Followed by a 5-Year Extension PeriodNCT05144256AGIOPhase 3Active not recruiting2024-05-03Actual
A Phase 3 Study Evaluating the Efficacy and Safety of OCS-01 Eyedrops Compared to Vehicle for the Treatment of Ocular Inflammation and Pain Following Cataract SurgeryNCT05147233OculisPhase 3Completed2023-06-22Actual
Study of APG-2575 in Patients With Relapsed/Refractory CLL/SLLNCT05147467Ascentage Pharma Group Inc.Phase 2Recruiting2026-12Estimated
A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal CancersNCT05152147Jazz PharmaceuticalsPhase 3Active not recruiting2026-07-15Actual
A Study of Oral ARD-101 in Patients With Prader-Willi SyndromeNCT05153434AARDPhase 2Completed2024-09-24Actual
IO102-IO103 in Combination With Pembrolizumab Versus Pembrolizumab Alone in Advanced Melanoma (IOB-013 / KN-D18)NCT05155254IO BiotechPhase 3Active not recruiting2025-05-30Actual
Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or RisdiplamNCT05156320Scholar Rock, Inc.Phase 3Completed2024-12-18Actual
ALTO-300 in Depression (ALTO-300-004)NCT05157945Alto NeurosciencePhase 2Completed2023-04-26Actual
Study to Evaluate the Safety, Tolerability of BCX9930 in Participants With Either Complement 3 Glomerulopathy (C3G), Immunoglobulin A Nephropathy (IgAN), or Primary Membranous Nephropathy (PMN)NCT05162066BioCryst PharmaceuticalsPhase 2Terminated2022-09-23Actual
A Long-Term Safety Study of PTC923 in Participants With PhenylketonuriaNCT05166161PTC TherapeuticsPhase 3Completed2026-07-21Actual
A Study to Evaluate the Efficacy and Safety of Mavacamten in Chinese Adults With Symptomatic Obstructive HCMNCT05174416LianBio LLCPhase 3Completed2023-03-06Actual
A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Not Regularly Transfused, Followed by a 5-Year Extension PeriodNCT05175105AGIOPhase 3Active not recruiting2024-12-13Actual
Study of SRF617 With AB928 (Etrumadenant) and AB122 (Zimberelimab) in Patients With Metastatic Castration Resistant Prostate CancerNCT05177770CHRSPhase 2Terminated2023-04-05Actual
Long-term Safety and Efficacy Profile of ABX464 in Subjects With Moderate to Severe Active Ulcerative ColitisNCT05177835ABVXPhase 2Active not recruiting2028-03Estimated
A Study of JZP150 in Adults With Posttraumatic Stress DisorderNCT05178316Jazz PharmaceuticalsPhase 2Completed2023-12-05Actual
A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral FluconazoleNCT05178862SCYXPhase 3Terminated2025-11-07Actual
Impact of CardiolRx on Myocardial Recovery in Patients With Acute MyocarditisNCT05180240CRDLPhase 2Completed2025-01-31Actual
A Multicenter, Phase 3 Randomized, Double-Blind, Vehicle-Controlled Study Evaluating the Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Pachyonychia CongenitaNCT05180708PVLAPhase 3Completed2023-06-30Actual
Safety and Efficacy of Brilaroxazine (RP5063) in SchizophreniaNCT05184335Reviva PharmaceuticalsPhase 3Recruiting2025-02Estimated
A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With VolanesorsenNCT05185843IONSPhase 3Active not recruiting2027-06Estimated
(Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic MastocytosisNCT05186753COGTPhase 2Active not recruiting2025-05-22Actual
Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCMNCT05186818CytokineticsPhase 3Completed2023-11-10Actual
Open-Label Proof of Concept Study of VP-315 in Basal Cell CarcinomaNCT05188729VRCAPhase 2Completed2024-04-15Actual
Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Participants With Specific Gene Defects in the MC4R PathwayNCT05194124RYTMPhase 3Completed2023-10-19Actual

Primary completion marks the end of data collection for the main study measures, not a results publication date.