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1,647 trials match your filters.
TrialSponsorPhaseStatusPrimary completion
A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid PolyneuropathyNCT05071300IONSPhase 3Active not recruiting2029-08Estimated
Parallel Arm Trial of AD109 and AD504 In Patients With OSANCT05071612ApnimedPhase 2Completed2022-07-20Actual
IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBCNCT05077709IO BiotechPhase 2Completed2025-11-30Actual
A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe HypertriglyceridemiaNCT05079919IONSPhase 3Completed2024-10-22Actual
Study to Evaluate the Safety and Efficacy of BF-200 ALA (Ameluz®) and BF-RhodoLED® in the Treatment of Moderate to Severe Acne Vulgaris With Photodynamic Therapy in AdultsNCT05080764BFRIPhase 2Completed2025-08-22Actual
A Study to Assess the Efficacy and Safety of REL-1017 as Monotherapy for Major Depressive Disorder (MDD)NCT05081167RLMDPhase 3Completed2022-09-13Actual
ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD)NCT05081245MapLight TherapeuticsPhase 2Completed2026-03-10Actual
The Symptomatic Cerebral Cavernous Malformation Trial of REC-994NCT05085561RXRXPhase 2Completed2025-06-30Actual
Study of ARO-APOC3 (Plozasiran) in Adults With Familial Chylomicronemia Syndrome (FCS)NCT05089084Arrowhead PharmaceuticalsPhase 3Completed2024-04-29Actual
EMANATE: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R PathwayNCT05093634RYTMPhase 3Completed2025-12-22Actual
A Study of PTC923 in Participants With PhenylketonuriaNCT05099640PTC TherapeuticsPhase 3Completed2023-04-03Actual
Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney DiseaseNCT05099770ProkidneyPhase 3Active not recruiting2029-12Estimated
An Exploratory Crossover Clinical Trial to Compare the Activity of Reproxalap and Lifitegrast in a Dry Eye Disease ChamberNCT05102409ALDXPhase 2Completed2021-10-25Actual
A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD)NCT05107128SUPNPhase 2Completed2024-09-04Actual
Study of ATH434 in Participants with Multiple System AtrophyNCT05109091Alterity TherapeuticsPhase 2Completed2024-11-28Actual
A 3-month Study to Compare the Safety of ONS-5010 in Vials Versus Pre-filled Syringe in Subjects With Visual Impairment Due to Retinal DisordersNCT05112861OTLKPhase 3Active not recruiting2027-12Estimated
A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects With Narcolepsy (ENCORE)NCT05113745AXSMPhase 3Completed2024-11-15Actual
BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants With Inadequate Response to C5 Inhibitor TherapyNCT05116774BioCryst PharmaceuticalsPhase 2Terminated2023-09-14Actual
BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants Not Receiving Other Complement Inhibitor TherapyNCT05116787BioCryst PharmaceuticalsPhase 2Terminated2023-09-18Actual
ALTO-100 in MDD and/or PTSDNCT05117632Alto NeurosciencePhase 2Completed2022-12-01Actual
ALTO-300 in DepressionNCT05118750Alto NeurosciencePhase 2Completed2023-05-05Actual
Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Dry Eye DiseaseNCT05119920Glaukos CorporationPhase 2Completed2022-07-27Actual
Study to Evaluate ARD-101 in Adults With ObesityNCT05121441AARDPhase 2Completed2022-11-09Actual
A Study To Assess the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essential Tremor (ET)NCT05122650Jazz PharmaceuticalsPhase 2Completed2024-05-30Actual
Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of PresbyopiaNCT05124275Glaukos CorporationPhase 2Completed2022-09-06Actual
Safety and Efficacy of AT-1501 in Patients With IgA Nephropathy (IgAN)NCT05125068Eledon PharmaceuticalsPhase 2Terminated2023-07-31Actual
Setrusumab vs Placebo for Osteogenesis ImperfectaNCT05125809RAREPhase 2, Phase 3Active not recruiting2025-10-20Actual
Lurbinectedin Monotherapy in Participants With Advanced or Metastatic Solid TumorsNCT05126433Jazz PharmaceuticalsPhase 2Terminated2023-12-20Actual
A Phase 2 Study to Evaluate the Safety, Efficacy and PK of Tildacerfont in Children Aged 2-17 Years With CAHNCT05128942Spruce BiosciencesPhase 2Terminated2025-01-31Actual
A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Participants With Familial Chylomicronemia Syndrome (FCS)NCT05130450IONSPhase 3Active not recruiting2028-02Estimated

Primary completion marks the end of data collection for the main study measures, not a results publication date.