NCT05093634Phase 3Completed

EMANATE: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway

Study sponsor: Rhythm Pharmaceuticals, Inc. · RYTM

Compare the available registry edits below. Primary completion is the date data collection ends for the main study measures; it does not tell you when results will be published.

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Primary completion2025-12-22Actual

Enrollment · participants296Actual

Source updated2026-08-06Last update listed in the registry record

Version history

Changes to this trial

Last 12 months

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Posted 2026-08-06 · 1 field changed

Recruitment status changed

− Before

~~Active not recruiting~~

+ After

Completed

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Posted 2026-02-10 · 4 fields changed

Participant count type changed

− Before

~~Estimated~~

+ After

Actual

Enrollment · participant count changed

− Before

~~400 participants (planned)~~

+ After

296 participants (actual)

Completion date type changed

− Before

~~Estimated~~

+ After

Actual

Primary completion date changed

− Before

~~Dec 2025~~

+ After

22 Dec 2025

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