Research directory

Clinical trials

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1,647 trials match your filters.
TrialSponsorPhaseStatusPrimary completion
A Phase 2 Study to Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients (INFRONT-2)NCT03987295ALECPhase 2Completed2024-06-05Actual
PROCLAIM: CX-072-002: Study of PD-L1 Probody Therapeutic CX-072 in Combination With Other Anticancer Therapy in Adults With Solid TumorsNCT03993379CytomX TherapeuticsPhase 2Terminated2020-05-21Actual
Efficacy and Safety Study of Mavorixafor in Participants With Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) SyndromeNCT03995108X4 PharmaceuticalsPhase 3Completed2025-12-23Actual
Efficacy and Safety of Losmapimod in Subjects With Facioscapulohumeral Muscular Dystrophy (FSHD)NCT04003974Fulcrum TherapeuticsPhase 2Completed2021-01-28Actual
Evaluation of Safety, Tolerability, and Changes in Biomarker and Clinical Outcome Assessments of Losmapimod for FSHD1 With ExtensionNCT04004000Fulcrum TherapeuticsPhase 2Terminated2024-10-31Actual
Study of Ad-RTS-hIL-12 + Veledimex in Combination With Cemiplimab in Subjects With Recurrent or Progressive GlioblastomaNCT04006119Alaunos TherapeuticsPhase 2Terminated2021-08-05Actual
A Study to Evaluate the Effectiveness and Safety of IONIS-FB-LRx, an Antisense Inhibitor of Complement Factor B, in Adult Participants With Primary IgA NephropathyNCT04014335IONSPhase 2Completed2024-02-08Actual
Study to Assess the Efficacy and Safety of Ublituximab and Umbralisib in Participants With Chronic Lymphocytic Leukemia (CLL) Currently Treated With Ibrutinib, Acalabrutinib or VenetoclaxNCT04016805TGTXPhase 2Terminated2022-05-22Actual
Efficacy and Safety Study of ABX464 as Maintenance Therapy in Patients With Moderate to Severe Ulcerative ColitisNCT04023396ABVXPhase 2Completed2023-02-23Actual
Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic GastroparesisNCT04028492Vanda PharmaceuticalsPhase 3Completed2025-02-21Actual
Phase 3 Study of Oral Ibrexafungerp (SCY-078) Vs. Placebo in Subjects With Recurrent Vulvovaginal Candidiasis (VVC)NCT04029116SCYXPhase 3Completed2021-09-01Actual
A Study of Nalbuphine (Extended Release) ER in Idiopathic Pulmonary Fibrosis (IPF) for Treatment of CoughNCT04030026Trevi TherapeuticsPhase 2Completed2022-05-27Actual
rVA576 in Adult Mild to Moderate Bullous Pemphigoid SubjectsNCT04035733AKARI TherapeuticsPhase 2Completed2020-03-12Actual
A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)NCT04042844BioRestorative TherapiesPhase 2Recruiting2026-12Estimated
A Study to Evaluate the Efficacy and Safety of KSI-301, an Anti-VEGF Antibody Biopolymer Conjugate, Versus Aflibercept in Patients With Neovascular (Wet) Age-Related Macular Degeneration.NCT04049266KODPhase 2, Phase 3Terminated2021-11-17Actual
Study Evaluating the Long-Term Safety and Efficacy of ABX464 in Patients With Moderate to Severe Rheumatoid ArthritisNCT04049448ABVXPhase 2Completed2023-01-23Actual
Study Evaluating Cemiplimab Alone and Combined With RP1 in Treating Advanced Squamous Skin CancerNCT04050436Replimune, Inc.Phase 2Active not recruiting2025-09Estimated
Hepcidin Mimetic in Patients With Polycythemia Vera (REVIVE)NCT04057040PTGXPhase 2Completed2023-02-14Actual
Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALSNCT04057898MediciNovaPhase 2, Phase 3Active not recruiting2027-04Estimated
Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx)NCT04059406IONSPhase 2Terminated2023-03-28Actual
A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular InsertNCT04061044OCULPhase 3Completed2020-02-10Actual
Velocity 2: An Anthrax Vaccine and Antibiotics Clinical StudyNCT04067011Emergent BioSolutionsPhase 2Completed2020-03-05Actual
Multimechanistic Treatment Over Time of Migraine Symptoms (MOVEMENT)NCT04068051AXSMPhase 3Completed2020-09-22Actual
Lentiviral-mediated Gene Therapy for Pediatric Patients With Fanconi Anemia Subtype ANCT04069533RCKTPhase 2Unknown2025-02Estimated
Phase 2a Evaluation of PLN-74809 on αvβ6 Receptor Occupancy Using PET Imaging in Participants With IPF/NCT04072315PLRXPhase 2Completed2022-06-27Actual
NEXAGON for the Treatment of Corneal Persistent Epithelial Defects Following Severe Ocular InjuriesNCT04081103Glaukos CorporationPhase 2Terminated2022-02-07Actual
Combination Margetuximab, Retifanlimab, Tebotelimab, and Chemotherapy Phase 2/3 Trial in HER2+ Gastric/GEJ CancerNCT04082364MacroGenicsPhase 2, Phase 3Completed2024-01-15Actual
Safety and Efficacy of ARQ-154 Foam in Subjects With Seborrheic DermatitisNCT04091646ARQTPhase 2Completed2020-08-18Actual
Study to Evaluate AD04 in Adults With Alcohol Use Disorder (AUD) and Selected Serotonin Transporter PolymorphismsNCT04101227Adial PharmaceuticalsPhase 3Completed2022-02-18Actual
A Study of OV101 in Individuals With Angelman Syndrome (AS)NCT04106557OVIDPhase 3Completed2020-11-02Actual

Primary completion marks the end of data collection for the main study measures, not a results publication date.