Research directory

Clinical trials

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1,647 trials match your filters.
TrialSponsorPhaseStatusPrimary completion
MRI Trial to exPlore the efficAcy and Safety of IMU-838 in Relapsing Remitting Multiple Sclerosis (EMPhASIS)NCT03846219Immunic AGPhase 2Active not recruiting2020-04-24Actual
QUILT-3.063: A Study of N-803, haNK and Avelumab in Patients With Merkel Cell Carcinoma That Has Progressed After Checkpoint TherapyNCT03853317IBRXPhase 2Terminated2021-09-29Actual
Extension Study of AG-348 in Adult Participants With Pyruvate Kinase Deficiency Previously Enrolled in AG-348-006 or AG348-C-007NCT03853798AGIOPhase 3Completed2024-07-03Actual
Clinical Study Comparing Two Models of a Travoprost Intraocular ImplantNCT03868124Glaukos CorporationPhase 3Completed2022-06-10Actual
Study to Evaluate the Efficacy and Safety of BCX7353 as an Oral Treatment for the Prevention of HAE Attacks in JapanNCT03873116BioCryst PharmaceuticalsPhase 3Completed2021-07-08Actual
VELOCITY: An Anthrax Vaccine Clinical StudyNCT03877926Emergent BioSolutionsPhase 3Completed2020-08-06Actual
Investigation of the Anti-tumor Effect of 2X-121 in Patients With Recurrent, Advanced Ovarian CancerNCT03878849Allarity TherapeuticsPhase 2Recruiting2027-03Estimated
The RENEW Trial: A Multi-Center, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Adaptive Phase 3 Clinical Trial to Assess the Safety and Efficacy of Subjects With Dry Eye DiseaseNCT03879863ALDXPhase 3Completed2019-10-04Actual
Clinical Outcomes in Narcolepsy and Cataplexy: An Evaluation of Reboxetine Treatment (CONCERT)NCT03881852AXSMPhase 2Completed2019-11-27Actual
RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line Cervical CancerNCT03894215AGENPhase 2Terminated2025-03-26Actual
Maximizing Outcomes in Treating Acute MigraineNCT03896009AXSMPhase 3Completed2019-12-10Actual
A Pivotal Study of Safety and Effectiveness of NanoKnife IRE for Stage 3 Pancreatic CancerNCT03899636ANGOPhase 3Active not recruiting2025-04Estimated
A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and FibrosisNCT03900429MDGLPhase 3Active not recruiting2028-01Estimated
IPH4102/Lacutamab Alone or in Combination With Chemotherapy in Patients With Advanced T Cell LymphomaNCT03902184Innate PharmaPhase 2Completed2026-01-08Actual
PRO 140 in Treatment-Experienced HIV-1 SubjectsNCT03902522CytoDyn, Inc.Phase 2, Phase 3Completed2020-05-18Actual
A Study to Evaluate the Efficacy and Safety of Maralixibat in Subjects With Progressive Familial Intrahepatic Cholestasis (MARCH-PFIC)NCT03905330MIRMPhase 3Completed2022-09-01Actual
A Multi-Center, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Clinical Trial of Reproxalap to Assess the Safety and Efficacy in Subjects With Dry Eye DiseaseNCT03916042ALDXPhase 2Completed2019-11-22Actual
Phase 2/3 Study Evaluating the Safety and Efficacy of PTX-022 in Treatment of Adults With Pachyonychia CongenitaNCT03920228PVLAPhase 2, Phase 3Completed2020-09-19Actual
An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular AtrophyNCT03921528Scholar Rock, Inc.Phase 2Completed2021-01-19Actual
Study to Evaluate the Effect of Filgotinib on Semen Parameters in Adult Males With Active Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, or Non-radiographic Axial SpondyloarthritisNCT03926195LKFTPhase 2Completed2020-08-14Actual
A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal CancerNCT03929666Jazz PharmaceuticalsPhase 2Completed2025-08-30Actual
APR-246 in Combination With Azacitidine for TP53 Mutated AML (Acute Myeloid Leukemia) or MDS (Myelodysplastic Syndromes) Following Allogeneic Stem Cell TransplantNCT03931291Aprea TherapeuticsPhase 2Completed2021-08-27Actual
Study of Cabozantinib in Combination With Nivolumab and Ipilimumab in Patients With Previously Untreated Advanced or Metastatic Renal Cell CarcinomaNCT03937219ExelixisPhase 3Active not recruiting2022-01-31Actual
Study of TVB-2640 in Subjects With Non-Alcoholic Steatohepatitis (NASH)NCT03938246SGMTPhase 2Completed2021-10-02Actual
Effect of Tumor Treating Fields (TTFields, 200 kHz) Concomitant With Weekly Paclitaxel for the Treatment of Recurrent Ovarian Cancer (ENGOT-ov50 / GOG-3029 / INNOVATE-3)NCT03940196NVCRPhase 3Completed2023-05-18Actual
Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Participants With Locally Advanced, Unresectable Pancreatic CancerNCT03941093Kyntra BioPhase 3Completed2024-06-11Actual
Safety, Tolerability and Pharmacodynamic Effect of Fazirsiran (TAK-999, ARO-AAT)NCT03945292Arrowhead PharmaceuticalsPhase 2Completed2021-11-08Actual
Study of Fazirsiran (TAK-999, ARO-AAT) in Patients With Alpha-1 Antitrypsin Deficiency Associated Liver Disease (AATD)NCT03946449Arrowhead PharmaceuticalsPhase 2Completed2022-04-28Actual
Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)NCT03955146Kyntra BioPhase 3Terminated2023-03-20Actual
A Placebo-Controlled Study Using VP-102 in the Treatment of External Genital WartsNCT03981822VRCAPhase 2Completed2020-05-21Actual

Primary completion marks the end of data collection for the main study measures, not a results publication date.