IBRX

ImmunityBio, Inc.

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24Trials in this database
19Recorded changes · last 12 months
Partial coverageOnly the trials and history collected so far

Research sample: selected versions from May 2023 onward plus a preceding baseline where available. Only selected fields were retained; endpoint measures were truncated to 300 characters. This is not complete trial or sponsor history. Daily snapshots begin when collection starts.

Completion dates · Pro

Which trial dates moved later?

Pro summarizes how far estimated completion dates moved later and counts trials with edits to their main study measures, using the history available here. View Pro features
TrialSponsorPhaseStatusPrimary completion
Preliminary Efficacy and Safety of INNO-206 Compared to Doxorubicin in Advanced Soft Tissue SarcomaNCT01514188IBRXPhase 2Completed2014-04-09Actual
Pilot Phase 2 Study to Investigate the Preliminary Efficacy and Safety of INNO-206 in Advanced Pancreatic CancerNCT01580397IBRXPhase 2Completed2013-05-13Actual
Phase 2 Study to Investigate the Efficacy and Safety of Aldoxorubicin in Subjects With GlioblastomaNCT02014844IBRXPhase 2Completed2016-12Actual
A Study to Investigate ALDOXORUBICIN in HIV-infected Subjects With Kaposi's SarcomaNCT02029430IBRXPhase 2Completed2016-04-25Actual
Phase 3 Study to Treat Patients With Soft Tissue SarcomasNCT02049905IBRXPhase 3Completed2017-05Actual
Efficacy and Safety of Aldoxorubicin Compared to Topotecan in Subjects With Metastatic Small Cell Lung CancerNCT02200757IBRXPhase 2Completed2017-05-15Actual
QUILT-3.009: Patients With Stage III (IIIB) or Stage (IV) Merkel Cell Carcinoma (MCC)NCT02465957IBRXPhase 2Terminated2018-03-19Actual
QUILT-3.032: A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination With ALT-803 (N-803) in Patients With BCG Unresponsive High Grade Non-Muscle Invasive Bladder CancerNCT03022825IBRXPhase 2, Phase 3Active not recruiting2024-10-01Actual
QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint InhibitorsNCT03228667IBRXPhase 2Active not recruiting2029-08-31Estimated
Nogapendekin Alfa Inbakicept for Advanced Non-Small Cell Lung CancerNCT03520686IBRXPhase 3Terminated2025-10-13Actual
QUILT-3.063: A Study of N-803, haNK and Avelumab in Patients With Merkel Cell Carcinoma That Has Progressed After Checkpoint TherapyNCT03853317IBRXPhase 2Terminated2021-09-29Actual
Combination Immunotherapy Plus Standard-of-Care Chemotherapy Versus Standard-of-Care Chemotherapy for the Treatment of Locally Advanced or Metastatic Pancreatic CancerNCT04390399IBRXPhase 2Active not recruiting2025-10-13Actual
A 2nd Generation E1/E2B/E3-Deleted Adenoviral COVID-19 Vaccine: The TCELL VACCINE TRIALNCT06022224IBRXPhase 2, Phase 3Terminated2022-06-23Actual
N-803 and PD-L1 t-haNK Combined With Bevacizumab for Recurrent or Progressive GlioblastomaNCT06061809IBRXPhase 2Active not recruiting2029-12-31Estimated
A Phase 2, Open-label, Single-arm Study Of Autologous M-CENK Adoptive Cell Therapy And N-803 (IL-15 Superagonist) In Combination With Gemcitabine In Participants With Recurrent Platinum-Resistant High-Grade Ovarian CancerNCT06710288IBRXPhase 2Recruiting2027-05Estimated
Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint InNCT06745908IBRXPhase 3Recruiting2028-09Estimated
Clinical Trial of Ablation Therapy in Participants With Intermediate-Risk Non-Muscle Invasive Papillary Bladder CancerNCT06829823IBRXPhase 2Not yet recruiting2026-11Estimated
A Study to Assess Anktiva in Patients With Long Covid-19.NCT07108036IBRXPhase 2Recruiting2026-10Estimated
A Study to Examine Anktiva for the Treatment of COVID-19.NCT07123727IBRXPhase 2Recruiting2027-03Estimated
Study of Relapsed/ Refractory B-cell Non- Hodgkin LymphomaNCT07125872IBRXPhase 2Recruiting2027-05-25Estimated
Study of CD19 t-haNK and NAI With Rituximab in Participants With Indolent Non-Hodgkin LymphomaNCT07477366IBRXPhase 2Not yet recruiting2027-12Estimated
NAI for Sepsis With Persistent LymphopeniaNCT07578558IBRXPhase 2Not yet recruiting2027-08-03Estimated
Phase 2 Study of NAI, HPV Vaccine, and Nab-Paclitaxel in HPV-Positive Oropharyngeal Cancer Followed by De-Intensified Radiation Compared With Standard ChemoradiationNCT07628062IBRXPhase 2Not yet recruiting2030-12-31Estimated
NAI Plus Standard of Care Compared With Placebo Plus Standard of Care in Critically Ill Adults With SepsisNCT07783789IBRXPhase 2Not yet recruiting2028-05-12Estimated

Latest recorded trial changes

· 5 fields changed

Participant count type changed

− Before

Estimated

+ After

Actual

Enrollment · participant count changed

− Before

1538 participants (planned)

+ After

102 participants (actual)

Completion date type changed

− Before

Estimated

+ After

Actual

Primary completion date changed

− Before

31 Oct 2026

+ After

13 Oct 2025

Recruitment status changed

− Before

Active not recruiting

+ After

Terminated

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· 1 field changed

Main study measure wording changed

Text changed; whether the study measures changed has not been verified. Saved text may be shortened.

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− Before

Measure: Objective Response Rate Measure: Prolongation of Overall Survival (OS) with NAI Therapy by ALC Response

+ After

Measure: ORR, defined as Investigator-assessed CR + PR per RECIST v1.1. Measure: Prolongation of OS with NAI therapy by ALC response, where: - OS is defined as the time from first study drug administration to death resulting from any cause. - ALC response is defined as achievement or maintenance of an on-treatment ALC ≥ 1,000 cells/μ

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· 1 field changed

Main study measure wording changed

Text changed; whether the study measures changed has not been verified. Saved text may be shortened.

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− Before

Measure: Objective Response Rate

+ After

Measure: Objective Response Rate Measure: Prolongation of Overall Survival (OS) with NAI Therapy by ALC Response

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· 1 field changed

Main study measure wording changed

Text changed; whether the study measures changed has not been verified. Saved text may be shortened.

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− Before

Measure: Progression Free Survival (PFS)

+ After

Measure: Progression Free Survival (PFS) Measure: Change in absolute lymphocyte count (ALC).

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