NCT03955146Phase 3Terminated

Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Study sponsor: Kyntra Bio

Compare the available registry edits below. Primary completion is the date data collection ends for the main study measures; it does not tell you when results will be published.

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Primary completion2023-03-20Actual

Enrollment · participants393Actual

Source updated2024-09-19Last update listed in the registry record

Version history

Changes to this trial

Last 12 months

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Study details

Conditions studied

Idiopathic Pulmonary Fibrosis

Treatments or interventions studied

PamrevlumabDrugAlso known as FG-3019
PlaceboDrug

Primary outcomes · main study measures

Read the study measures

measure: DB Period (Main Study Cohort): Change From Baseline in FVC at Week 48; description: FVC is a standard pulmonary function test used to quantify respiratory muscle weakness. FVC was the volume of air that could forcibly be blown out after full inspiration in the upright position, measured in liters. Least square (LS) mean and standard error (SE) were calculated using mixed model for repeated measures (MMRM).; timeFrame: Baseline, Week 48; measure: DB Period (Japan Extension Cohort): Change From Baseline in FVC at Week 48; description: FVC is a standard pulmonary function test used to quantify respiratory muscle weakness. FVC was the volume of air that could forcibly be blown out after full inspiration in the upright position, measured in liters.; timeFrame: Baseline, Week 48

History coverage

Research sample: selected versions from May 2023 onward plus a preceding baseline where available. Only selected fields were retained; endpoint measures were truncated to 300 characters. This is not complete trial or sponsor history. Daily snapshots begin when collection starts.

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