A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)
NCT06985147 · Disc Medicine, Inc
Recruitment statusRecorded edit
− Previous value
Recruiting
+ Updated value
Active not recruiting
IRON
Disc Medicine, Inc
Company identity checked against sources
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5Trials in this database
9Recorded changes · last 12 months
Partial coverageOnly the trials and history collected so far
Research sample: selected versions from May 2023 onward plus a preceding baseline where available. Only selected fields were retained; endpoint measures were truncated to 300 characters. This is not complete trial or sponsor history. Daily snapshots begin when collection starts.
Completion dates · Pro
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Pro summarizes how far estimated completion dates moved later and counts trials with edits to their main study measures, using the history available here. View Pro features
Included trials
Check company identity source| Trial | Sponsor | Phase | Status | Primary completion |
|---|---|---|---|---|
| Study of Bitopertin to Evaluate the Safety, Tolerability, Efficacy, and PPIX Concentrations in Participants With EPPNCT05308472 | IRON | Phase 2 | Completed | 2024-02-20Actual |
| HELIOS: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP or XLPNCT05883748 | IRON | Phase 2, Phase 3 | Enrolling by invitation | 2028-06Estimated |
| Study of Bitopertin in Participants With EPP or XLP (APOLLO)NCT06910358 | IRON | Phase 3 | Active not recruiting | 2026-09Estimated |
| A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)NCT06985147 | IRON | Phase 2 | Active not recruiting | 2027-02Estimated |
| Study of DISC-0974-201 in Participants With IBD and AnemiaNCT07368972 | IRON | Phase 2 | Recruiting | 2026-10Estimated |
Latest recorded trial changes
Study of Bitopertin in Participants With EPP or XLP (APOLLO)
NCT06910358 · Disc Medicine, Inc
Recruitment statusRecorded edit
− Previous value
Recruiting
+ Updated value
Active not recruiting
Study of Bitopertin in Participants With EPP or XLP (APOLLO)
NCT06910358 · Disc Medicine, Inc
Primary completion dateRecorded edit
− Previous value
2026-10
+ Updated value
2026-09
Study of Bitopertin in Participants With EPP or XLP (APOLLO)
NCT06910358 · Disc Medicine, Inc
Enrollment · participant countRecorded edit
− Previous value
count: 150; type: ESTIMATED
+ Updated value
count: 183; type: ACTUAL
Study of Bitopertin in Participants With EPP or XLP (APOLLO)
NCT06910358 · Disc Medicine, Inc
Participant count typeRecorded edit
− Previous value
Estimated
+ Updated value
Actual
Study of DISC-0974-201 in Participants With IBD and Anemia
NCT07368972 · Disc Medicine, Inc
Recruitment statusRecorded edit
− Previous value
Not yet recruiting
+ Updated value
Recruiting
HELIOS: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP or XLP
NCT05883748 · Disc Medicine, Inc
Enrollment · participant countRecorded edit
− Previous value
count: 200; type: ESTIMATED
+ Updated value
count: 230; type: ESTIMATED
A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)
NCT06985147 · Disc Medicine, Inc
Enrollment · participant countRecorded edit
− Previous value
count: 20; type: ESTIMATED
+ Updated value
count: 60; type: ESTIMATED
Study of Bitopertin to Evaluate the Safety, Tolerability, Efficacy, and PPIX Concentrations in Participants With EPP
NCT05308472 · Disc Medicine, Inc
Primary outcomes · main study measuresText edit · unverified significance
− Previous value
measure: Percent change from baseline in whole blood metal-free PPIX levels
+ Updated value
measure: Percent Change From Baseline in Whole Blood Metal-free PPIX Levels
Check registry source · The saved outcome text may be shortened. Check the source for full wording.