NCT06510816Phase 3Active not recruiting

A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of Vonaprument (Formerly ANX007) in Participants With Dry Age-Related Macular Degeneration (AMD) With Geographic Atrophy (GA)

Study sponsor: Annexon, Inc. · ANNX

Compare the available registry edits below. Primary completion is the date data collection ends for the main study measures; it does not tell you when results will be published.

Primary completion2026-10-31Estimated
Enrollment · participants659Actual
Source updated2026-05-04Last update listed in the registry record
Version history

Changes to this trial

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· 1 field changed

Primary outcomes · main study measures

Text edit · unverified significance
− Previous value

measure: Proportion of patients experiencing a best corrected visual acuity (BCVA) ≥15-letter loss from baseline through the primary timepoint as assessed by the Early Treatment Diabetic Retinopathy Study (ETDRS) chart at any two consecutive visits.

+ Updated value

measure: Proportion of Participants Experiencing a Best Corrected Visual Acuity (BCVA) ≥15-letter Loss from Baseline Through Month 15 as Assessed by the Early Treatment Diabetic Retinopathy Study (ETDRS) Chart at Any Two Consecutive Visits

The saved outcome text may be shortened. Check the source for full wording.

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· 3 fields changed

Participant count type

Recorded edit
− Previous value

Estimated

+ Updated value

Actual

Enrollment · participant count

Recorded edit
− Previous value

count: 630; type: ESTIMATED

+ Updated value

count: 659; type: ACTUAL

Recruitment status

Recorded edit
− Previous value

Recruiting

+ Updated value

Active not recruiting

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