NCT06000410Phase 3Completed

A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee

Compare the available registry edits below. Primary completion is the date data collection ends for the main study measures; it does not tell you when results will be published.

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Primary completion2025-08-15Actual

Enrollment · participants594Actual

Source updated2026-04-21Last update listed in the registry record

Version history

Changes to this trial

Last 12 months

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Posted 2025-12-23 · 3 fields changed

Participant count type changed

− Before

~~Estimated~~

+ After

Actual

Enrollment · participant count changed

− Before

~~474 participants (planned)~~

+ After

594 participants (actual)

Recruitment status changed

− Before

~~Active not recruiting~~

+ After

Completed

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Posted 2025-10-16 · 2 fields changed

Completion date type changed

− Before

~~Estimated~~

+ After

Actual

Primary completion date changed

− Before

~~Sep 2025~~

+ After

15 Aug 2025

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Study details

Conditions studied

Knee Osteoarthritis

Treatments or interventions studied

Amniotic Suspension AllograftBiological
PlaceboDrug

Primary outcomes · main study measures

Read the study measures

measure: The difference in change from baseline in WOMAC Pain scale at 6 months between ASA- and placebo-treated patients; description: The WOMAC is widely used in the evaluation of hip and knee OA. It is a self-administered questionnaire consisting of 24 items divided into 3 subscales: pain, stiffness, and physical function. The WOMAC measure has been used in clinical trials to evaluate the efficacy of surgical treatments, medicinal and biological products, devices, and physical therapies.; timeFrame: Baseline to Week 26

History coverage

Research sample: selected versions from May 2023 onward plus a preceding baseline where available. Only selected fields were retained; endpoint measures were truncated to 300 characters. This is not complete trial or sponsor history. Daily snapshots begin when collection starts.

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