Clinical trials / NCT05818553
NCT05818553Phase 2, phase 3Active not recruiting

A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE)

Study sponsor: Praxis Precision Medicines

Compare the available registry edits below. Primary completion is the date data collection ends for the main study measures; it does not tell you when results will be published.

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Primary completion2025-11-12Actual
Enrollment · participants77Estimated
Source updated2026-01-29Last update listed in the registry record
Version history

Changes to this trial

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· 5 fields changed

Primary outcomes · main study measures

Text edit · unverified significance
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measure: To assess the effect of PRAX-562 on the frequency of countable motor seizures in pediatric participants with DEEs

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measure: PART A (Cohorts 1 and 2) RDB: To evaluate the safety and tolerability of PRAX 562 in pediatric participants with SCN2A- and SCN8A- DEEs; measure: PART B (Cohorts 1 and 2) OLE: To evaluate the long-term safety and tolerability of PRAX-562 in pediatric participants with DEEs

The saved outcome text may be shortened. Check the source for full wording.

Enrollment · participant count

Recorded edit
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count: 100; type: ESTIMATED

+ Updated value

count: 77; type: ESTIMATED

Completion date type

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Estimated

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Actual

Primary completion date

Recorded edit
− Previous value

2026-03-23

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2025-11-12

Recruitment status

Recorded edit
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Recruiting

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Active not recruiting

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