NCT05257408Phase 3Active not recruiting

Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer

Study sponsor: Corcept Therapeutics

Compare the available registry edits below. Primary completion is the date data collection ends for the main study measures; it does not tell you when results will be published.

Primary completion2025-03-31Actual
Enrollment · participants381Actual
Source updated2026-09-25Last update listed in the registry record
Version history

Changes to this trial

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· 2 fields changed

Main study measure wording changed

Text changed; whether the study measures changed has not been verified. Saved text may be shortened.

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− Before

Measure: Progression-free Survival as Assessed by BICR Description: Time from randomization until the time of first documented progressive disease (PD) by Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1, or death due to any cause, whichever occurs first Time frame: Up to 24 months from enrollment of the last patient Measure: Overall survival Description: Time from randomization to death by any cause Time frame: Up to 24 months from enrollment of the last patient

+ After

Measure: Progression-free Survival (PFS) as Assessed by Blinded Independent Central Review (BICR) Description: PFS was assessed as the time from randomization until the time of first documented progressive disease (PD) or death due to any cause, whichever occurs first. Progression is defined using Response Evaluation Criteria In Solid Tumors Criteria (RECIST v1.1), as a 20% increase in the sum of the longest diameter of target lesions, or an unequivocal progression in a non-target lesion, or the appearance of new lesions. Time frame: Up to 20 months Measure: Overall Survival Description: Overall survival (OS) was assessed as the time from randomization to death by any cause. The data values are Kaplan-Meier estimates. Time frame: Up to 32 months

Primary completion date changed

− Before

24 Mar 2025

+ After

31 Mar 2025

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