NCT04636229Phase 3Completed

Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee

Compare the available registry edits below. Primary completion is the date data collection ends for the main study measures; it does not tell you when results will be published.

Open ClinicalTrials.gov record CSV export · Pro

Primary completion2023-07-30Actual

Enrollment · participants516Actual

Source updated2025-10-16Last update listed in the registry record

Version history

Changes to this trial

Last 12 months

Pro unlocks the full available history and CSV export. View Pro features

Posted 2025-10-16 · 3 fields changed

Participant count type changed

− Before

~~Estimated~~

+ After

Actual

Enrollment · participant count changed

− Before

~~474 participants (planned)~~

+ After

516 participants (actual)

Recruitment status changed

− Before

~~Active not recruiting~~

+ After

Completed

Check registry source

Study details

Conditions studied

Knee Osteoarthritis

Treatments or interventions studied

Amniotic Suspension AllograftBiological
PlaceboDrug

Primary outcomes · main study measures

Read the study measures

measure: The difference in change from baseline in WOMAC Pain scale at 6 months between ASA- and placebo-treated patients; description: The Western Ontario and McMaster Universities (WOMAC®) Osteoarthritis Index is a questionnaire that measures pain, stiffness, and function both independently and collectively, using a Likert 3.1, 5-point scale. The Likert Scale uses the following descriptors for all items: none, mild moderate, severe, and extreme, corresponding to an ordinal scale of 0-4. Higher scores on the WOMAC indicate worse pain, stiffness, and functional limitations.; timeFrame: Baseline to Week 26

History coverage

Research sample: selected versions from May 2023 onward plus a preceding baseline where available. Only selected fields were retained; endpoint measures were truncated to 300 characters. This is not complete trial or sponsor history. Daily snapshots begin when collection starts.

How to read this history