NCT03131154Phase 3Completed

SOLACE Trial - A Phase 3 Trial in Subjects With Non-infectious Anterior-uveitis.

Study sponsor: Aldeyra Therapeutics, Inc. · ALDX

Compare the available registry edits below. Primary completion is the date data collection ends for the main study measures; it does not tell you when results will be published.

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Primary completion2019-04-19Actual

Enrollment · participants123Actual

Source updated2025-02-10Last update listed in the registry record

Version history

Changes to this trial

Last 12 months

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Study details

Conditions studied

Non-infectious Anterior Uveitis

Treatments or interventions studied

ADX-102 Ophthalmic Solution (0.5%)DrugAlso known as Reproxalap
Vehicle of ADX-102 Ophthalmic SolutionDrugAlso known as Vehicle of Reproxlap

Primary outcomes · main study measures

Read the study measures

measure: Number of Subjects Who Meet Time to Clearance of Anterior Chamber Cells; description: Time to clearance of anterior chamber cells was defined as the time from initiation of study drug to when a cell count of 0 was achieved and maintained (without cell count increases to \>0) to Week 4 and without rescue or discontinuation due to rescue prior to Week 4. Anterior chamber cell count is the number of cells visible within the anterior chamber of the eye, measured using a slit lamp and following SUN (Standardization of Uveitis Nomenclature) where a cell count \<1 is Grade 0 (absent) and a cell count of \>50 is Grade 4+ (severe).; timeFrame: The efficacy assessment period was 4 weeks; baseline was defined as Day 1.

History coverage

Research sample: selected versions from May 2023 onward plus a preceding baseline where available. Only selected fields were retained; endpoint measures were truncated to 300 characters. This is not complete trial or sponsor history. Daily snapshots begin when collection starts.

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