NCT02143648Phase 2, phase 3Completed

Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus

Compare the available registry edits below. Primary completion is the date data collection ends for the main study measures; it does not tell you when results will be published.

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Primary completion2015-07Actual

Enrollment · participants373Actual

Source updated2025-05-21Last update listed in the registry record

Version history

Changes to this trial

Last 12 months

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No recorded changes are available for this view and time period. Our history may be incomplete; this does not establish that the trial stayed unchanged.

Study details

Conditions studied

Uremic Pruritus; Pruritus

Treatments or interventions studied

nalbuphine HCl ER tablets 60 mg BIDDrugAlso known as nalbuphine ER
nalbuphine HCl ER tablets 120mg BIDDrugAlso known as nalbuphine ER
Placebo tablets BIDDrugAlso known as sugar pill

Primary outcomes · main study measures

measure: Change From Baseline to the Evaluation Period in Itch on the 0-10 Itch Numerical Rating Scale; description: The evaluation period was defined as the average itch score over weeks 7 and 8 following initiation of treatment. A negative change form baseline (Evaluation Period - Baseline) signified inmprovement.; timeFrame: 8 weeks

History coverage

Research sample: selected versions from May 2023 onward plus a preceding baseline where available. Only selected fields were retained; endpoint measures were truncated to 300 characters. This is not complete trial or sponsor history. Daily snapshots begin when collection starts.

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