NCT02129660Phase 2Completed

Comparator Study of the Effect of Glycopyrrolate and Glycopyrronium in Subjects With Axillary Hyperhidrosis

Study sponsor: Journey Medical Corporation

Compare the available registry edits below. Primary completion is the date data collection ends for the main study measures; it does not tell you when results will be published.

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Primary completion2015-01Actual

Enrollment · participants105Actual

Source updated2025-09-17Last update listed in the registry record

Version history

Changes to this trial

Last 12 months

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Study details

Conditions studied

Hyperhidrosis

Treatments or interventions studied

Dose 1 of glycopyrrolate, 2.0% QDDrugAlso known as DRM04B
Dose 2 of glycopyrrolate, 3.0% QDDrugAlso known as DRM04B
Dose 1 of glycopyrronium, 2.5% QDDrugAlso known as DRM04
Dose 2 of glycopyrronium, 3.75% QDDrugAlso known as DRM04

Primary outcomes · main study measures

Read the study measures

measure: Percentage of Subjects Who Have a Minimum 2-grade Improvement in HDSS From Baseline at Week 4; description: HDSS is a disease specific diagnostic tool that provides a qualitative measure of the severity of the subjects' condition based on how it affects daily activities. 1 (Best), 2, 3, 4 (Worst); timeFrame: Baseline - Week 4/ET; measure: Percentage of Subjects Who Have a Minimum 1-grade Improvement in HDSS From Baseline at Week 4; timeFrame: Baseline - Week 4; measure: Percentage of Subjects Who Have a Minimum 1-grade Improvement in HDSS From Baseline at Week 6; timeFrame: Baseline - Week 6; measure: Absolute Change in the Gravimetrically Measured Sweat Production From Baseline to Week 4; description: Subjects are acclimated to the environment for 30 minutes. Dry gauze is weighed. The dry gauze is then applied to the subject's axilla with the arm down by the subject's side or on their lap during the 5-minute period of sweat production. The gauze with the sweat is then weighed. The difference between the Weight of the gauze with sweat and the dry gauze is the gravimetric sweat measurement in mg/5min.; timeFrame: Baseline - Week 4; measure: Absolute Change in the Gravimetrically Measured Sweat Production From Baseline to Week 6; timeFrame: Baseline - Week 6

History coverage

Research sample: selected versions from May 2023 onward plus a preceding baseline where available. Only selected fields were retained; endpoint measures were truncated to 300 characters. This is not complete trial or sponsor history. Daily snapshots begin when collection starts.

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