NCT05376150Phase 2Completed

A Study to Evaluate the Safety, Tolerability and Efficacy of XEN1101 in Major Depressive Disorder

Study sponsor: Xenon Pharmaceuticals Inc. · XENE

Compare the available registry edits below. Primary completion is the date data collection ends for the main study measures; it does not tell you when results will be published.

Primary completion2023-09-18Actual
Enrollment · participants168Actual
Source updated2026-09-21Last update listed in the registry record
Version history

Changes to this trial

Last 12 months
Pro unlocks the full available history and CSV export. View Pro features

· 1 field changed

Main study measure wording changed

Text changed; whether the study measures changed has not been verified. Saved text may be shortened.

Compare wording
− Before

Measure: Change in Montgomery-Åsberg Depression Rating Scale (MADRS) score. Measure: Frequency and severity of treatment-emergent adverse events (TEAEs), treatment-emergent serious adverse events (SAEs), and TEAEs leading to treatment discontinuations.

+ After

Measure: Change in Montgomery-Åsberg Depression Rating Scale (MADRS) Score.

Check registry source