*,:after,:before{--tw-border-spacing-x:0;--tw-border-spacing-y:0;--tw-translate-x:0;--tw-translate-y:0;--tw-rotate:0;--tw-skew-x:0;--tw-skew-y:0;--tw-scale-x:1;--tw-scale-y:1;--tw-pan-x: ;--tw-pan-y: ;--tw-pinch-zoom: ;--tw-scroll-snap-strictness:proximity;--tw-gradient-from-position: ;--tw-gradient-via-position: ;--tw-gradient-to-position: ;--tw-ordinal: ;--tw-slashed-zero: ;--tw-numeric-figure: ;--tw-numeric-spacing: ;--tw-numeric-fraction: ;--tw-ring-inset: ;--tw-ring-offset-width:0px;--tw-ring-offset-color:#fff;--tw-ring-color:rgba(59,130,246,.5);--tw-ring-offset-shadow:0 0 #0000;--tw-ring-shadow:0 0 #0000;--tw-shadow:0 0 #0000;--tw-shadow-colored:0 0 #0000;--tw-blur: ;--tw-brightness: ;--tw-contrast: ;--tw-grayscale: ;--tw-hue-rotate: ;--tw-invert: ;--tw-saturate: ;--tw-sepia: ;--tw-drop-shadow: ;--tw-backdrop-blur: ;--tw-backdrop-brightness: ;--tw-backdrop-contrast: ;--tw-backdrop-grayscale: ;--tw-backdrop-hue-rotate: ;--tw-backdrop-invert: ;--tw-backdrop-opacity: ;--tw-backdrop-saturate: ;--tw-backdrop-sepia: ;--tw-contain-size: ;--tw-contain-layout: ;--tw-contain-paint: ;--tw-contain-style: }::backdrop{--tw-border-spacing-x:0;--tw-border-spacing-y:0;--tw-translate-x:0;--tw-translate-y:0;--tw-rotate:0;--tw-skew-x:0;--tw-skew-y:0;--tw-scale-x:1;--tw-scale-y:1;--tw-pan-x: ;--tw-pan-y: ;--tw-pinch-zoom: ;--tw-scroll-snap-strictness:proximity;--tw-gradient-from-position: ;--tw-gradient-via-position: ;--tw-gradient-to-position: ;--tw-ordinal: ;--tw-slashed-zero: ;--tw-numeric-figure: ;--tw-numeric-spacing: ;--tw-numeric-fraction: ;--tw-ring-inset: ;--tw-ring-offset-width:0px;--tw-ring-offset-color:#fff;--tw-ring-color:rgba(59,130,246,.5);--tw-ring-offset-shadow:0 0 #0000;--tw-ring-shadow:0 0 #0000;--tw-shadow:0 0 #0000;--tw-shadow-colored:0 0 #0000;--tw-blur: ;--tw-brightness: ;--tw-contrast: ;--tw-grayscale: ;--tw-hue-rotate: ;--tw-invert: ;--tw-saturate: ;--tw-sepia: ;--tw-drop-shadow: ;--tw-backdrop-blur: ;--tw-backdrop-brightness: ;--tw-backdrop-contrast: ;--tw-backdrop-grayscale: ;--tw-backdrop-hue-rotate: ;--tw-backdrop-invert: ;--tw-backdrop-opacity: ;--tw-backdrop-saturate: ;--tw-backdrop-sepia: ;--tw-contain-size: ;--tw-contain-layout: ;--tw-contain-paint: ;--tw-contain-style: }/*! tailwindcss v3.4.17 | MIT License | https://tailwindcss.com*/*,:after,:before{border:0 solid #e5e7eb;box-sizing:border-box}:after,:before{--tw-content:""}:host,html{line-height:1.5;-webkit-text-size-adjust:100%;font-family:ui-sans-serif,system-ui,sans-serif,Apple Color Emoji,Segoe UI Emoji,Segoe UI Symbol,Noto Color Emoji;font-feature-settings:normal;font-variation-settings:normal;-moz-tab-size:4;-o-tab-size:4;tab-size:4;-webkit-tap-highlight-color:transparent}body{line-height:inherit;margin:0}hr{border-top-width:1px;color:inherit;height:0}abbr:where([title]){-webkit-text-decoration:underline dotted;text-decoration:underline dotted}h1,h2,h3,h4,h5,h6{font-size:inherit;font-weight:inherit}a{color:inherit;text-decoration:inherit}b,strong{font-weight:bolder}code,kbd,pre,samp{font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,Liberation Mono,Courier New,monospace;font-feature-settings:normal;font-size:1em;font-variation-settings:normal}small{font-size:80%}sub,sup{font-size:75%;line-height:0;position:relative;vertical-align:baseline}sub{bottom:-.25em}sup{top:-.5em}table{border-collapse:collapse;border-color:inherit;text-indent:0}button,input,optgroup,select,textarea{color:inherit;font-family:inherit;font-feature-settings:inherit;font-size:100%;font-variation-settings:inherit;font-weight:inherit;letter-spacing:inherit;line-height:inherit;margin:0;padding:0}button,select{text-transform:none}button,input:where([type=button]),input:where([type=reset]),input:where([type=submit]){-webkit-appearance:button;background-color:transparent;background-image:none}:-moz-focusring{outline:auto}:-moz-ui-invalid{box-shadow:none}progress{vertical-align:baseline}::-webkit-inner-spin-button,::-webkit-outer-spin-button{height:auto}[type=search]{-webkit-appearance:textfield;outline-offset:-2px}::-webkit-search-decoration{-webkit-appearance:none}::-webkit-file-upload-button{-webkit-appearance:button;font:inherit}summary{display:list-item}blockquote,dd,dl,figure,h1,h2,h3,h4,h5,h6,hr,p,pre{margin:0}fieldset{margin:0}fieldset,legend{padding:0}menu,ol,ul{list-style:none;margin:0;padding:0}dialog{padding:0}input::-moz-placeholder,textarea::-moz-placeholder{color:#9ca3af;opacity:1}input::placeholder,textarea::placeholder{color:#9ca3af;opacity:1}[role=button],button{cursor:pointer}:disabled{cursor:default}audio,canvas,embed,iframe,img,object,svg,video{display:block;vertical-align:middle}img,video{height:auto;max-width:100%}[hidden]:where(:not([hidden=until-found])){display:none}body{font-family:-apple-system,BlinkMacSystemFont,Segoe UI,sans-serif}h1,h2,h3{font-weight:600;letter-spacing:-.025em;--tw-text-opacity:1;color:rgb(15 23 42/var(--tw-text-opacity,1))}h1{font-size:1.875rem;line-height:2.25rem}@media (min-width:768px){h1{font-size:2.25rem;line-height:2.5rem}}h2{font-size:1.5rem;line-height:2rem}h3{font-size:1.125rem;line-height:1.75rem}a,button,input,select,textarea{transition-duration:.15s;transition-property:color,background-color,border-color,text-decoration-color,fill,stroke;transition-timing-function:cubic-bezier(.4,0,.2,1)}a:hover{--tw-text-opacity:1;color:rgb(29 78 216/var(--tw-text-opacity,1))}a:focus-visible,button:focus-visible,input:focus-visible,select:focus-visible,summary:focus-visible,textarea:focus-visible{outline:2px solid #2563eb;outline-offset:3px}label{display:block;font-size:.875rem;font-weight:600;line-height:1.25rem;margin-bottom:.5rem;--tw-text-opacity:1;color:rgb(71 85 105/var(--tw-text-opacity,1))}input:not([type=hidden]):not([type=checkbox]),select,textarea{border-radius:.375rem;border-width:1px;width:100%;--tw-border-opacity:1;border-color:rgb(203 213 225/var(--tw-border-opacity,1));--tw-bg-opacity:1;background-color:rgb(255 255 255/var(--tw-bg-opacity,1));font-size:.875rem;line-height:1.25rem;padding:.75rem;--tw-text-opacity:1;color:rgb(15 23 42/var(--tw-text-opacity,1))}input[type=checkbox]{accent-color:#1d4ed8;height:1rem;width:1rem}.auth-form{margin-bottom:1.25rem;margin-top:1.75rem}.card h1{font-size:1.875rem;line-height:2.25rem}@media (min-width:768px){.card h1{font-size:2.25rem;line-height:2.5rem}}.card>p{font-size:.875rem;line-height:1.5rem;margin-bottom:1rem;margin-top:1rem}.card>.btn{border-width:1px;width:100%;--tw-border-opacity:1;border-color:rgb(203 213 225/var(--tw-border-opacity,1))}.auth-form>.btn{margin-top:.75rem;width:100%}.form-field input{margin-top:.5rem}.card{margin-left:auto;margin-right:auto;max-width:32rem;padding-bottom:1rem;padding-top:1rem}.btn-primary{background-color:rgb(15 23 42/var(--tw-bg-opacity,1))}.btn-primary,.btn-primary:hover{--tw-bg-opacity:1;--tw-text-opacity:1;color:rgb(255 255 255/var(--tw-text-opacity,1))}.btn-primary:hover{background-color:rgb(30 64 175/var(--tw-bg-opacity,1))}.form-field{margin-bottom:1.25rem}.input{border-radius:.375rem;border-width:1px;width:100%;--tw-border-opacity:1;border-color:rgb(203 213 225/var(--tw-border-opacity,1));--tw-bg-opacity:1;background-color:rgb(255 255 255/var(--tw-bg-opacity,1));font-size:.875rem;line-height:1.25rem;padding:.75rem}.shell{margin-left:auto;margin-right:auto;max-width:80rem;padding-left:1.25rem;padding-right:1.25rem}@media (min-width:768px){.shell{padding-left:2.5rem;padding-right:2.5rem}}.main-content{min-height:24rem;padding-bottom:2rem;padding-top:2rem}@media (min-width:768px){.main-content{padding-bottom:3rem;padding-top:3rem}}.site-header{border-bottom-width:1px;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1));--tw-bg-opacity:1;background-color:rgb(255 255 255/var(--tw-bg-opacity,1))}.brand{align-items:center;display:inline-flex;font-size:1.25rem;font-weight:700;gap:.25rem;letter-spacing:-.025em;line-height:1.75rem;white-space:nowrap;--tw-text-opacity:1;color:rgb(15 23 42/var(--tw-text-opacity,1))}.main-nav{display:flex;gap:1.25rem;--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.btn,.main-nav{align-items:center;font-size:.875rem;line-height:1.25rem}.btn{border-radius:.375rem;display:inline-flex;font-weight:600;gap:.75rem;justify-content:center;padding:.75rem 1.25rem;white-space:nowrap}.btn-dark{background-color:rgb(15 23 42/var(--tw-bg-opacity,1))}.btn-dark,.btn-dark:hover{--tw-bg-opacity:1;--tw-text-opacity:1;color:rgb(255 255 255/var(--tw-text-opacity,1))}.btn-dark:hover{background-color:rgb(30 64 175/var(--tw-bg-opacity,1))}.btn-outline{border-width:1px;--tw-border-opacity:1;border-color:rgb(203 213 225/var(--tw-border-opacity,1));--tw-bg-opacity:1;background-color:rgb(255 255 255/var(--tw-bg-opacity,1));--tw-text-opacity:1;color:rgb(51 65 85/var(--tw-text-opacity,1))}.btn-outline:hover{--tw-border-opacity:1;border-color:rgb(71 85 105/var(--tw-border-opacity,1))}.btn-sm{font-size:.75rem;line-height:1rem;padding:.5rem .75rem}.eyebrow{font-size:.875rem;font-weight:500;line-height:1.25rem;margin-bottom:.75rem;--tw-text-opacity:1;color:rgb(71 85 105/var(--tw-text-opacity,1))}.hero{max-width:56rem;padding-bottom:1.5rem}.hero h1{font-size:1.875rem;letter-spacing:-.025em;line-height:2.25rem;line-height:1.25}@media (min-width:768px){.hero h1{font-size:2.25rem;line-height:2.5rem}}.hero-copy{font-size:1rem;line-height:1.75rem;margin-top:1rem;--tw-text-opacity:1;color:rgb(71 85 105/var(--tw-text-opacity,1))}.hero-copy,.hero-search{max-width:42rem}.hero-search{border-bottom-width:1px;-moz-column-gap:.75rem;column-gap:.75rem;display:grid;margin-top:1.5rem;row-gap:.25rem;--tw-border-opacity:1;border-color:rgb(148 163 184/var(--tw-border-opacity,1));padding-bottom:.5rem}.hero-search input:not([type=hidden]):not([type=checkbox]){border-width:0;flex:1 1 0%;min-width:0;padding-left:.25rem;padding-right:.25rem}.stats-grid{border-bottom-width:1px;border-top-width:1px;display:grid;grid-template-columns:repeat(2,minmax(0,1fr));margin-top:.5rem;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1))}@media (min-width:768px){.stats-grid{grid-template-columns:repeat(4,minmax(0,1fr))}}.stats-grid>div{padding-bottom:1rem;padding-right:1rem;padding-top:1rem}.stats-grid strong{display:block;font-size:1.25rem;font-weight:600;line-height:1.75rem;margin-bottom:.25rem;--tw-text-opacity:1;color:rgb(15 23 42/var(--tw-text-opacity,1))}.stats-grid small,.stats-grid span{display:block;font-size:.75rem;line-height:1.25rem;--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.stats-grid.three{grid-template-columns:repeat(1,minmax(0,1fr))}@media (min-width:640px){.stats-grid.three{grid-template-columns:repeat(3,minmax(0,1fr))}}.stats-grid.three strong{font-size:1.25rem;line-height:1.75rem;margin-top:.5rem}.section-gap{margin-top:2.25rem}@media (min-width:768px){.section-gap{margin-top:2.5rem}}.section-heading{align-items:baseline;display:flex;flex-wrap:wrap;gap:1rem;justify-content:space-between;margin-bottom:1.5rem}.muted{line-height:1.625;--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.section-heading p{font-size:.875rem;line-height:1.25rem;margin-top:.5rem}.change-card{border-bottom-width:1px;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1));padding-bottom:1.5rem;padding-top:1.5rem}.redline{display:grid;gap:1.25rem}@media (min-width:768px){.redline{grid-template-columns:repeat(2,minmax(0,1fr))}}.redline>div{font-size:.875rem;line-height:1.5rem;overflow-wrap:break-word;padding-bottom:.25rem;padding-left:.75rem;padding-top:.25rem}.before{border-color:rgb(251 113 133/var(--tw-border-opacity,1));border-left-width:2px;color:rgb(51 65 85/var(--tw-text-opacity,1))}.after,.before{--tw-border-opacity:1;--tw-text-opacity:1}.after{border-color:rgb(5 150 105/var(--tw-border-opacity,1));border-left-width:2px;color:rgb(15 23 42/var(--tw-text-opacity,1))}.redline-label{display:block;font-weight:500;line-height:1rem;margin-bottom:.5rem}.badge,.redline-label{font-size:.75rem;--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.badge{display:inline-block;font-weight:400;line-height:1.25rem}.mono{font-family:ui-monospace,SFMono-Regular,Menlo,monospace}.source{--tw-text-opacity:1;color:rgb(29 78 216/var(--tw-text-opacity,1))}.conflict-note{border-left-width:2px;margin-bottom:1.5rem;--tw-border-opacity:1;border-color:rgb(217 119 6/var(--tw-border-opacity,1));padding-left:1rem}.conflict-note,.conflict-note h2{--tw-text-opacity:1;color:rgb(69 26 3/var(--tw-text-opacity,1))}.conflict-note h2{font-size:1.125rem;line-height:1.75rem;margin-bottom:.75rem}.conflict-note p{font-size:.875rem;line-height:1.75rem}.coverage-note{border-left-width:2px;margin-bottom:1.5rem;margin-top:1.5rem;--tw-border-opacity:1;border-color:rgb(203 213 225/var(--tw-border-opacity,1));font-size:.875rem;line-height:1.5rem;padding-left:1rem;--tw-text-opacity:1;color:rgb(71 85 105/var(--tw-text-opacity,1))}.coverage-note a{--tw-text-opacity:1;color:rgb(29 78 216/var(--tw-text-opacity,1))}.page-heading{margin-bottom:1.75rem}.page-heading p{line-height:1.75rem;margin-top:1rem;--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.detail-title{font-size:1.5rem;line-height:2rem;line-height:1.25;max-width:64rem}@media (min-width:768px){.detail-title{font-size:1.875rem;line-height:2.25rem}}.breadcrumb{font-size:.75rem;line-height:1rem;margin-bottom:1.75rem;--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.filter-bar{align-items:flex-end;border-bottom-width:1px;display:flex;flex-wrap:wrap;gap:1rem;margin-bottom:1.25rem;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1));padding-bottom:1.25rem}.filter-bar select{max-width:20rem}.results-caption{font-size:.75rem;line-height:1rem;margin-bottom:1rem;--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.table-wrap{border-bottom-width:1px;border-top-width:1px;overflow-x:auto;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1))}table{border-collapse:collapse;font-size:.875rem;line-height:1.25rem;text-align:left;width:100%}th{font-size:.75rem;font-weight:600;line-height:1rem;padding:.75rem 1rem;white-space:nowrap;--tw-text-opacity:1;color:rgb(71 85 105/var(--tw-text-opacity,1))}td{border-top-width:1px;--tw-border-opacity:1;border-color:rgb(241 245 249/var(--tw-border-opacity,1));padding:1rem;vertical-align:top}.record-table td[data-label="Trial / program"]{min-width:16rem}td .row-title{display:block;font-weight:500;line-height:1.5rem;margin-bottom:.5rem;max-width:28rem;--tw-text-opacity:1;color:rgb(30 41 59/var(--tw-text-opacity,1))}td small{display:block;font-size:.75rem;line-height:1rem;margin-top:.5rem}.empty,td small{--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.empty{font-size:.875rem;line-height:1.75rem;padding:2.5rem;text-align:center}.pagination{align-items:center;display:flex;flex-wrap:wrap;font-size:.75rem;gap:1rem;justify-content:space-between;line-height:1rem;margin-top:1.5rem;--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.directory-grid{-moz-column-gap:2rem;column-gap:2rem;display:grid}@media (min-width:768px){.directory-grid{grid-template-columns:repeat(3,minmax(0,1fr))}}.directory-card{border-bottom-width:1px;display:block;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1));padding-bottom:1.25rem;padding-top:1.25rem}.directory-card:hover{--tw-border-opacity:1;border-color:rgb(100 116 139/var(--tw-border-opacity,1))}.directory-card h2{font-size:1.125rem;line-height:1.75rem}.ticker{display:inline-block;font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,Liberation Mono,Courier New,monospace;font-size:.75rem;font-weight:600;line-height:1rem;--tw-text-opacity:1;color:rgb(30 64 175/var(--tw-text-opacity,1))}.detail-grid{display:grid;gap:2rem}@media (min-width:1024px){.detail-grid{grid-template-columns:minmax(0,1fr) 300px}}.detail-sidebar{align-self:flex-start;border-left-width:1px;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1));padding-left:1.5rem}.detail-sidebar dt{font-size:.75rem;font-weight:500;line-height:1rem;margin-bottom:.5rem;margin-top:1.5rem;--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.detail-sidebar dd{font-size:.875rem;line-height:1.5rem;margin-bottom:1.5rem;overflow-wrap:break-word}.upgrade-note{border-bottom-width:1px;border-top-width:1px;margin-bottom:1.25rem;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1));font-size:.875rem;line-height:1.25rem;padding-bottom:.75rem;padding-top:.75rem;--tw-text-opacity:1;color:rgb(51 65 85/var(--tw-text-opacity,1))}.upgrade-note a{font-weight:600}.panel{align-self:flex-start;border-top-width:1px;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1));padding-bottom:1rem;padding-top:1rem}.price-card{display:flex;flex-direction:column;padding-bottom:1.5rem;padding-top:1.5rem}.pricing-grid{border-bottom-width:1px;border-top-width:1px;display:grid;gap:2.5rem;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1))}@media (min-width:1024px){.pricing-grid{grid-template-columns:repeat(3,minmax(0,1fr))}}.price-card h2{font-size:2.25rem;line-height:2.5rem;margin-top:.5rem}.price-card h2 span{font-size:.75rem;font-weight:400;letter-spacing:0;line-height:1rem}.price-card h2 span,.price-card>p{--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.price-card>p{font-size:.875rem;line-height:1.25rem;margin-top:1rem}.price-card ul{flex:1 1 0%;margin-bottom:2rem;margin-top:2rem}.price-card ul>:not([hidden])~:not([hidden]){--tw-space-y-reverse:0;margin-bottom:calc(1rem*var(--tw-space-y-reverse));margin-top:calc(1rem*(1 - var(--tw-space-y-reverse)))}.price-card ul{font-size:.875rem;line-height:1.25rem;--tw-text-opacity:1;color:rgb(71 85 105/var(--tw-text-opacity,1))}.price-card li{border-bottom-width:1px;--tw-border-opacity:1;border-color:rgb(241 245 249/var(--tw-border-opacity,1));padding-bottom:.75rem}.price-card small{font-size:.75rem;line-height:1rem;margin-top:1rem;text-align:center;--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.price-card.featured{border-width:0;--tw-shadow:0 0 #0000;--tw-shadow-colored:0 0 #0000;box-shadow:var(--tw-ring-offset-shadow,0 0 #0000),var(--tw-ring-shadow,0 0 #0000),var(--tw-shadow)}.narrow{margin-left:auto;margin-right:auto;max-width:48rem}.workspace-nav{border-bottom-width:1px;display:flex;gap:1.75rem;margin-bottom:2rem;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1));font-size:.875rem;line-height:1.25rem;--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.workspace-nav a{padding-bottom:1rem}.workspace-nav .active{border-bottom-width:2px;--tw-border-opacity:1;border-color:rgb(15 23 42/var(--tw-border-opacity,1));font-weight:600;--tw-text-opacity:1;color:rgb(15 23 42/var(--tw-text-opacity,1))}.watch-row{align-items:center;border-top-width:1px;display:flex;justify-content:space-between;--tw-border-opacity:1;border-color:rgb(241 245 249/var(--tw-border-opacity,1));font-size:.875rem;line-height:1.25rem;padding-bottom:1rem;padding-top:1rem}.watch-row small{display:block;font-size:.75rem;line-height:1rem;margin-top:.25rem;--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.check-label{align-items:center;display:flex;font-size:.875rem;font-weight:400;gap:.75rem;line-height:1.25rem}.secret-panel{background-color:rgb(255 251 235/var(--tw-bg-opacity,1));margin-bottom:1.5rem}.code-sample,.secret-panel{border-radius:.5rem;--tw-bg-opacity:1;padding:1rem}.code-sample{background-color:rgb(15 23 42/var(--tw-bg-opacity,1));font-size:.75rem;line-height:1rem;overflow:auto;--tw-text-opacity:1;color:rgb(226 232 240/var(--tw-text-opacity,1))}.prose-page{margin-left:auto;margin-right:auto;max-width:48rem}.prose-page section{margin-bottom:2.25rem}.prose-page section p{line-height:2rem;margin-top:1rem;--tw-text-opacity:1;color:rgb(71 85 105/var(--tw-text-opacity,1))}.glossary-list{border-top-width:1px;margin-top:2rem;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1))}.glossary-list a{border-bottom-width:1px;display:flex;justify-content:space-between;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1));padding-bottom:1.25rem;padding-top:1.25rem}.site-footer{border-top-width:1px;margin-top:3rem;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1));--tw-bg-opacity:1;background-color:rgb(255 255 255/var(--tw-bg-opacity,1))}.footer-nav{-moz-column-gap:2rem;column-gap:2rem;display:grid;font-size:.75rem;grid-template-columns:repeat(2,minmax(0,1fr));line-height:1rem;row-gap:1rem;--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}@media (min-width:768px){.footer-nav{grid-template-columns:repeat(4,minmax(0,1fr))}}.fineprint{font-size:.75rem;line-height:1.25rem;--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.flash{background-color:rgb(241 245 249/var(--tw-bg-opacity,1));color:rgb(15 23 42/var(--tw-text-opacity,1));font-size:.875rem;line-height:1.25rem;margin-bottom:1.5rem;padding:.75rem 1rem}.flash,.flash.error{--tw-bg-opacity:1;--tw-text-opacity:1}.flash.error{background-color:rgb(255 241 242/var(--tw-bg-opacity,1));color:rgb(136 19 55/var(--tw-text-opacity,1))}.skip-link{height:1px;margin:-1px;overflow:hidden;padding:0;position:absolute;width:1px;clip:rect(0,0,0,0);border-width:0;white-space:nowrap}.skip-link:focus{height:auto;margin:0;overflow:visible;position:static;width:auto;clip:auto;position:absolute;white-space:normal;z-index:50;--tw-bg-opacity:1;background-color:rgb(255 255 255/var(--tw-bg-opacity,1));padding:1rem}.header-inner{align-items:center;display:flex;flex-wrap:wrap;gap:1.5rem;padding-bottom:.75rem;padding-top:.75rem}.account-nav{align-items:center;display:flex;font-size:.875rem;gap:1rem;line-height:1.25rem;margin-left:auto}.account-nav button,.account-nav>a:not(.btn),.main-nav a{align-items:center;display:inline-flex;min-height:2.75rem}.main-nav [aria-current=page],.mobile-menu [aria-current=page]{font-weight:600;--tw-text-opacity:1;color:rgb(15 23 42/var(--tw-text-opacity,1));text-decoration-line:underline;text-underline-offset:8px}.mobile-menu{display:none}.btn{min-height:2.75rem}.hero-label{grid-column:1/-1;margin-bottom:0}.hero-search{grid-template-columns:minmax(0,1fr) auto}.hero-search input{font-size:1rem;line-height:1.5rem}.changes-list{border-top-width:1px;--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1))}.coverage-note a:hover,.source:hover{text-decoration-line:underline}.coverage-note,.page-heading p,.prose-page section p{max-width:70ch}.prose-page section p{line-height:1.75rem}.detail-grid>*,.directory-grid>*,.page-heading>*,.pricing-grid>*,.stats-grid>*{min-width:0}.breadcrumb,.coverage-note,.detail-sidebar,.directory-card,.page-heading,.panel,.record-table td,.watch-row{overflow-wrap:anywhere}.mono,.stats-grid strong{font-variant-numeric:tabular-nums}.workspace-nav a{align-items:center;display:inline-flex;min-height:2.75rem;white-space:nowrap}.remove-watch{font-size:.875rem;line-height:1.25rem;min-height:2.75rem;padding-left:.75rem;padding-right:.75rem;--tw-text-opacity:1;color:rgb(71 85 105/var(--tw-text-opacity,1))}.watch-row{gap:1rem}.watch-row form{flex-shrink:0}.footer-nav{font-size:.875rem;line-height:1.25rem;row-gap:.25rem}.footer-nav a{align-items:center;display:inline-flex}.check-label,.footer-nav a{min-height:2.75rem}.check-label input{flex-shrink:0}.empty{padding:2rem 1rem;text-align:left}.card p a,.prose-page p a{--tw-text-opacity:1;color:rgb(29 78 216/var(--tw-text-opacity,1));text-decoration-line:underline;text-underline-offset:2px}.visible{visibility:visible}.static{position:static}.relative{position:relative}.col-span-2{grid-column:span 2/span 2}.mx-auto{margin-left:auto;margin-right:auto}.my-3{margin-bottom:.75rem;margin-top:.75rem}.\!mb-8{margin-bottom:2rem!important}.\!mt-0{margin-top:0!important}.mb-2{margin-bottom:.5rem}.mb-3{margin-bottom:.75rem}.mb-4{margin-bottom:1rem}.mb-5{margin-bottom:1.25rem}.mb-6{margin-bottom:1.5rem}.mb-8{margin-bottom:2rem}.ml-auto{margin-left:auto}.mt-1{margin-top:.25rem}.mt-2{margin-top:.5rem}.mt-3{margin-top:.75rem}.mt-4{margin-top:1rem}.mt-5{margin-top:1.25rem}.mt-6{margin-top:1.5rem}.mt-8{margin-top:2rem}.block{display:block}.inline-block{display:inline-block}.flex{display:flex}.table{display:table}.grid{display:grid}.hidden{display:none}.min-h-11{min-height:2.75rem}.w-full{width:100%}.max-w-lg{max-width:32rem}.max-w-sm{max-width:24rem}.grow{flex-grow:1}.cursor-pointer{cursor:pointer}.flex-wrap{flex-wrap:wrap}.items-center{align-items:center}.justify-between{justify-content:space-between}.gap-3{gap:.75rem}.gap-6{gap:1.5rem}.gap-8{gap:2rem}.whitespace-nowrap{white-space:nowrap}.break-all{word-break:break-all}.border-y{border-bottom-width:1px;border-top-width:1px}.border-t{border-top-width:1px}.border-slate-100{--tw-border-opacity:1;border-color:rgb(241 245 249/var(--tw-border-opacity,1))}.border-slate-200{--tw-border-opacity:1;border-color:rgb(226 232 240/var(--tw-border-opacity,1))}.bg-white{--tw-bg-opacity:1;background-color:rgb(255 255 255/var(--tw-bg-opacity,1))}.py-10{padding-bottom:2.5rem;padding-top:2.5rem}.py-2{padding-bottom:.5rem;padding-top:.5rem}.py-3{padding-bottom:.75rem;padding-top:.75rem}.text-lg{font-size:1.125rem;line-height:1.75rem}.text-sm{font-size:.875rem;line-height:1.25rem}.text-xl{font-size:1.25rem;line-height:1.75rem}.text-xs{font-size:.75rem;line-height:1rem}.font-medium{font-weight:500}.font-normal{font-weight:400}.font-semibold{font-weight:600}.capitalize{text-transform:capitalize}.leading-6{line-height:1.5rem}.text-rose-700{--tw-text-opacity:1;color:rgb(190 18 60/var(--tw-text-opacity,1))}.text-slate-400{--tw-text-opacity:1;color:rgb(148 163 184/var(--tw-text-opacity,1))}.text-slate-500{--tw-text-opacity:1;color:rgb(100 116 139/var(--tw-text-opacity,1))}.text-slate-600{--tw-text-opacity:1;color:rgb(71 85 105/var(--tw-text-opacity,1))}.text-slate-700{--tw-text-opacity:1;color:rgb(51 65 85/var(--tw-text-opacity,1))}.text-slate-800{--tw-text-opacity:1;color:rgb(30 41 59/var(--tw-text-opacity,1))}.antialiased{-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale}.filter{filter:var(--tw-blur) var(--tw-brightness) var(--tw-contrast) var(--tw-grayscale) var(--tw-hue-rotate) var(--tw-invert) var(--tw-saturate) var(--tw-sepia) var(--tw-drop-shadow)}@media(max-width:1023px){.header-inner{display:block;position:relative}.header-inner>.brand{max-width:calc(100% - 5rem);min-height:44px}.account-nav,.main-nav{display:none}.mobile-menu{display:block}.mobile-menu summary{align-items:center;cursor:pointer;display:flex;font-size:.875rem;font-weight:600;gap:.5rem;min-height:44px;position:absolute;right:2.5rem;top:.75rem}.mobile-menu summary:after{content:"+";font-size:1.25rem;font-weight:400}.mobile-menu[open] summary:after{content:"−"}.mobile-menu nav{border-top:1px solid #e2e8f0;display:grid;gap:.25rem 1.5rem;grid-template-columns:repeat(2,minmax(0,1fr));margin-top:.75rem;padding:1rem 0}.mobile-menu nav a,.mobile-menu nav button{align-items:center;display:flex;font-size:.875rem;min-height:44px}.detail-sidebar{border-left:0;border-top:1px solid #e2e8f0;padding-left:0;padding-top:1.5rem}.workspace-grid>aside{order:-1}}@media(max-width:767px){.shell{padding-left:1rem;padding-right:1rem}.mobile-menu summary{right:1rem}.hero h1,h1{font-size:1.875rem;line-height:1.2}h2{font-size:1.25rem;line-height:1.4}.detail-title{font-size:1.5rem;line-height:1.3}input:not([type=hidden]):not([type=checkbox]),select,textarea{font-size:1rem;min-height:48px}input::-moz-placeholder{color:#64748b;opacity:1}input::placeholder{color:#64748b;opacity:1}.filter-bar{display:grid;gap:1.25rem 1rem;grid-template-columns:repeat(2,minmax(0,1fr))}.filter-bar>div:first-of-type{grid-column:1/-1}.filter-bar>div{min-width:0}.filter-bar select{max-width:none}.filter-bar>a{align-items:center;display:flex;min-height:44px}.hero-copy{line-height:1.6}.hero-search{border:0;gap:.5rem;grid-template-columns:minmax(0,1fr);padding:0}.hero-search input:not([type=hidden]):not([type=checkbox]){border:1px solid #cbd5e1;border-radius:.375rem;padding:.75rem;width:100%}.hero-search .btn{margin-top:.25rem}.badge,.detail-sidebar dt,.redline-label,.results-caption,.stats-grid small,.stats-grid span{font-size:.875rem;line-height:1.5}.stats-grid>div{padding:1rem .5rem 1rem 0}.section-heading{gap:.75rem}.change-card{padding:1.25rem 0}.change-card>div:first-child{align-items:baseline;gap:.5rem .75rem}.change-card>div:first-child>a{align-items:center;display:flex;margin-left:0;min-height:44px}.change-card>div:last-child{font-size:.875rem;line-height:1.6}.redline{gap:1rem}.redline>div{font-size:1rem;line-height:1.6}.workspace-nav{flex-wrap:wrap;gap:1rem}.workspace-nav a{font-size:.875rem;padding-bottom:.75rem}.pricing-grid{gap:0}.price-card+.price-card{border-top:1px solid #e2e8f0}.price-card{padding:1.5rem 0}.price-card small{line-height:1.6;text-align:left}.price-card ul{flex:initial;margin:1.5rem 0}.price-card li{border:0;padding:0}.directory-card{padding:1.25rem 0}.form-field{margin-bottom:1.5rem}.card a:not(.btn),.card>p{line-height:1.75}.card>p>a{display:inline-block;padding:.25rem 0}.site-footer{margin-top:2.5rem}.site-footer .brand{font-size:1.125rem}.footer-nav{gap:0 1rem;width:100%}.pagination{gap:1rem}.pagination>span{order:3;width:100%}}@media(prefers-reduced-motion:reduce){*{scroll-behavior:auto!important;transition:none!important}}@media(max-width:767px){.change-card .source,.record-table .source,.record-table button{align-items:center;display:inline-flex;min-height:44px}.stats-grid.three{grid-template-columns:repeat(2,minmax(0,1fr))}.stats-grid.three>div:last-child{grid-column:1/-1}}@media(max-width:1023px){.table-wrap{border-bottom:0;overflow:visible}.record-table,.record-table tbody{display:block;width:100%}.record-table thead{height:1px;margin:-1px;overflow:hidden;position:absolute;width:1px;clip:rect(0,0,0,0);white-space:nowrap}.record-table tr{border-bottom:1px solid #e2e8f0;display:grid;gap:1rem;grid-template-columns:repeat(2,minmax(0,1fr));padding:1.5rem 0}.record-table td{border:0;display:block;font-size:.875rem;line-height:1.5;min-width:0;padding:0;white-space:normal}.record-table td:first-child,.record-table td[colspan],.record-table td[data-label="Drug / sponsor"],.record-table td[data-label=Event],.record-table td[data-label=Evidence],.record-table td[data-label=Indication]{grid-column:1/-1;min-width:0}.record-table td[data-label]:before{color:#64748b;content:attr(data-label);display:block;font-family:-apple-system,BlinkMacSystemFont,Segoe UI,sans-serif;font-size:.75rem;font-weight:400;line-height:1.5;margin-bottom:.375rem}.record-table td[data-label="Trial / program"]:before{display:none}.record-table td .row-title{font-size:1rem;line-height:1.5;margin-bottom:.5rem;max-width:none}.record-table summary{font-size:.875rem;min-height:44px;padding:.75rem 0}.record-table details p{font-size:.875rem;line-height:1.6;overflow-wrap:anywhere}.record-table td small{font-size:.875rem;line-height:1.5}}textarea{resize:vertical}@media(min-width:1024px){.events-table{table-layout:fixed}.events-table th:first-child{width:12%}.events-table th:nth-child(2){width:22%}.events-table th:nth-child(3),.events-table th:nth-child(4){width:20%}.events-table th:nth-child(5){width:26%}.events-table details p,.events-table summary{font-size:.875rem;line-height:1.6}}@media (min-width:640px){.sm\:col-span-1{grid-column:span 1/span 1}}@media (min-width:768px){.md\:col-span-2{grid-column:span 2/span 2}.md\:grid-cols-2{grid-template-columns:repeat(2,minmax(0,1fr))}}@media (min-width:1024px){.lg\:col-span-3{grid-column:span 3/span 3}}